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Below is a list of currently enrolling Clinical Trials at the Appalachian Clinical and Translational Science Institute (ACTSI). If you would like additional information about a specific trial, you can call the contact number provided and speak with a study coordinator.
Additional information about each trial can be obtained at ClinicalTrials.gov by clicking on the descriptions below
For more information regarding Active Clinical Trials, contact our Medical Director of Clinical Trials - Usha Murughiyan (304) 691-1836.
Active Clinical Trials |
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Study ID | PI | Specialty | Disease Process | Currently Enrolling | Description | Contact Information |
NCT04173273 |
Sundaram |
Gastrointestinal |
Crohn's Disease |
Yes |
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NCT03616821 |
Sundaram |
Gastrointestinal |
Ulcerative Colitis |
Yes |
[D5271C0001 - EXPEDITION] An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis |
|
NCT03759288 |
Sundaram |
Gastrointestinal |
Crohn's Disease |
Yes |
(D5271C0001 - Intrepid) An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease |
|
NCT04396236 |
Lopez |
Neurology |
Pediatric Migraine |
Yes |
(PIONEER-PEDS1) A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine |
|
NCT04396574 |
Lopez |
Neurology |
Pediatric Migraine |
Yes |
(PIONEER-PEDS2) A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine |
|
TP-201920 |
Gentile |
Orthopedic Surgery |
Podiatric Screw Placement |
Yes |
(Trauma Screw) An Observational Study to Gather Real-World Data on the Tyber Medical Trauma Screw System |
|
P255-501 |
Lopez |
Neurology |
Pediatric Migraine |
Yes |
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NCT04821310 |
Villa |
Gastrointestinal |
Erosive Esophagitis |
Yes |
||
NTC04938830 |
Shields |
Pediatrics |
RSV |
Yes |
||
NCT03887715 |
Holroyd |
Mental Health |
Treatment-Resistant Depression |
Yes |
||
964144 |
Sundaram |
Gastrointestinal |
NIH/RO1 Grant |
Yes |
Regulation of Intestinal Nutrient and Electrolyte Transport in Chronic Disease |
|
NCT0564172 |
Lopez |
Neurology |
Pediatric Migraine |
Yes |
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NCT05242471 |
Sundaram |
Gastrointestinal |
Chron's Disease |
Yes |
||
NCT04965675 |
Lopez |
Neurology |
Pediatric Migraine |
Yes |
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N/A |
Sundaram/Haynes |
COBRE |
Development of Organoids |
Yes |
Regulation of Intestinal Nutrient and Electrolyte Transport in chronic Disease |
Jennifer Haynes |
N/A |
Sundaram/Singh |
COBRE |
Adipose Derived Secretome/Absorption |
Yes |
Adipose derived secretome (ADS) uniquely regulates intestinal epithelial cell nutrient absorption during obesity. |
Soudamani Singh |
N/A |
Sundaram / Palaniappan |
COBRE |
Adenoma / Colorectal Cancer |
Yes |
Mechanism of regulation of Down regulated Adenoma (DRA) transporter in obesity associated colitis. |
Bala Palaniappan |
499630 |
Koester |
Orthopedic Surgery |
Metacarpal Tendon Repair |
Yes |
Humanitarian Use Device (HUD) for surgical repair of metacarpal tendon. |
Dr. Koester/ Mary Beth Cordle |
463451 |
Koester |
Orthopedic Surgery |
Metacarpal Tendon Repair |
Yes |
Humanitarian Use Device (HUD) for surgical repair of metacarpal tendon. |
Dr. Koester/ Mary Beth Cordle |
964144 |
Sundaram / Arthur |
RO1 / COBRE |
Nutrient and Electrolyte Transport |
Yes |
Regulation of Intestinal Nutrient and Electrolyte Transport in Chronic Disease |
Subha Arthur |
N/A |
Sundaram / Cecchetti |
DCTS / COBRE |
Integrating Biology |
Yes |
Marshall University School of Medicine Informatics for Integrating to the Biology to the Bedside (I2B2) |
Alfred Cecchetti |
N/A |
Sundaram / Cecchetti |
DCTS / COBRE |
Helicobacter Pylori |
Yes |
Helicobacter Pylori ( H. Pylori) in Apppalachia |
Jacqueline Cavendish |
N/A |
Sundaram / Cecchetti |
DCTS / COBRE |
Metabolic Syndrome Classification |
Yes |
Classification of Metabolic Syntrome Patients Using a Data Warehouse Developed Algorithm |
Alfred Cecchetti |
Updated on May 11, 2023
For more information regarding Upcoming Clinical Trials, contact our Medical Director of Clinical Trials - Usha Murughiyan (304) 691-1836.
Active Clinical Trials |
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Study ID | PI | Specialty | Disease Process | Currently Enrolling | Description | Contact Information |
N/A |
Sundaram |
Gastrointestinal |
Peripheral Artery Disease |
Pending Activation |
ICE-PAD: Improving Care via the HER in PAD |
|
N/A |
Sundaram |
Gastrointestinal |
Hepatitis |
Pending Activation |
HCV Patient Identification Algorithm |
|
NCT05164172/ (PCORI) |
Lopez |
Neurology |
Pediatric Migraine |
Pending Activation |
PCORI Grant with Cincinnati Children's Hospital - CBT via Telehealth + Amitriptyline Compared to CBT via Telehealth: Pediatric Migraine Prevention |
Updated on May 11, 2023.
For more information regarding Upcoming Clinical Trials, contact our Medical Director of Clinical Trials - Usha Murughiyan (304) 691-1836.
Completed Trials
Study ID | PI | Specialty | Disease Process | Comments | Description | Contact |
NCT03971071 |
Ferguson |
Neurology |
Multiple Sclerosis |
Closed - Moved to Historical Lab |
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NCT03926130 |
Sundaram |
Gastrointestinal |
Chrohn's Disease |
Closed - Moved to Historical Lab |
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NCT04329780 |
Nease |
Bariatrics |
Multicenter Study to Evaluateosos |
Closed - Moved to Historical Lab |
||
N/A |
Ferguson |
Neurology |
Chronic Migraine |
Closed - Moved to Historical Lab |
(TRIUMPH) Preventive Treatment of migraine: Outcomes for Patients in real-world Healthcare systems |
|
N/A |
Sundaram |
Gastrointestinal |
COVID |
Closed - Moved to Historical Lab |
Activated Charcoal to Treat COVID-19 Patients to Improve Health Outcomes |
|
NCT03996369 |
Sundaram |
Gastrointestinal |
Ulcerative Colitis |
Closed - Moved to Historical Lab |
||
NCT03028740 |
Sundaram |
Gastrointestinal |
NASH |
Closed - Moved to Historical Lab |
||
CLP-001 |
Webb |
Rheumatology |
Rheumatoid Arthritis |
Closed - Moved to Historical Lab |
(RESET-RA) A Randomized, Sham-Controlled, Double-Bline Study of Vagus Nerve Stimulation for Moderate-to-Severe Rheumatoid Arthritis |
|
NCT03290560 |
Nolte |
Neurology |
Acute Ischemic Stroke |
Closed - Moved to Historical Lab |
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NCT03012776 |
Phan |
Neurosurgery |
Spondylolisthesis |
Long Term Follow-Up |
(TOPS IDE) A Clinical Study to Assess the Safety and Effectiveness of the Premia Spine TOPS™ System. |
|
NCT04032093 |
Keblawi |
OB/GYN |
RSV |
Long Term Follow-Up |
||
NCT03537508 |
Shields |
Pediatrics |
Meningitis |
Long Term Follow - Up |
||
NCT03466411 |
Sundaram |
Gastrointestinal |
Ulcerative Colitis |
Closed- Moved to Historical Lab |
||
N/A |
Frandah |
Gastrointestinal |
Pancreatitis |
Closed- Moved to Historical Lab |
(DESTIN) - Randomized Trial Comparing Immediate Endoscopic Necrosectomy vs. Step-up Endoscopic Interventions in Necrotizing Pancreatitis |
|
NCT04140305 |
Ferguson |
Neurology |
Multiple Sclerosis |
Closed-Moved to Historical Lab |
||
NCT04320940 |
Massey |
NICU |
Neonatal Seizures |
Closed-Moved to Historical Lab |
|
|
NCT04144738 |
Sundaram |
Gastrointestinal |
Colon Cancer Screening |
Closed-Moved to Historical Lab |
|
|
TP-201920
|
Gentile |
Orthopedic Surgery |
Podiatric Screw Placement |
Closed-Moved to Historical Lab |
(Trauma Screw) An Observational Study to Gather Real-World Data on the Tyber Medical Trauma Screw System |
|
NCT03616821 |
Sundaram |
Gastrointestinal |
Ulcerative Colitis |
Closed-Moved to Historical Lab |
[D5271C0001 - EXPEDITION] An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis |
|
NCT03759288 |
Sundaram |
Gastrointestinal |
Crohn's Disease |
Closed-Moved to Historical Lab |
(D5271C0001 - Intrepid) An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease |
Updated on May 11, 2023