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Jung Han Kim, PhD

Research Interests

My long-term research interest is in understanding the etiology and mechanisms underlying Type 2 diabetes and obesity, concomitantly related diseases. Type 2 diabetes is the most common form of human diabetes, accounting for over 90% of cases. Obesity at such epidemic proportions creates serious public health problems. Both diseases, furthermore, are associated with chronic complications and cardiovascular disease, increasing morbidity as well as mortality.

Mao X, Dillon KD, McEntee MF, Saxton AM, and Kim JH. Islet insulin secretion, b-cell mass, and energy balance in a polygenic mouse model of Type 2 diabetes with obesity. Journal of Inborn Errors of Metabolism & Screening 2014: 1-6.

Stewart TP, Mao X, Aqqad MN, Uffort D, Dillon KD, Saxton AM, and Kim JH. Subcongenic analysis of tabw2 obesity QTL on mouse chromosome 6. BMC Genet 2012, 13(1): 81.

Fletcher SJ, Kalupahana NS, Soltani-Bejnood M, Kim JH, Saxton AM, Wasserman DH, De Taeye B, Voy BH, Quignard-Boulange A, Moustaid-Moussa N. Transgenic mice overexpressing Renin exhibit glucose intolerance and diet-genotype interactions. Front Endocrinol (Lausanne) 2012, 3: 166.

Kim JH and Saxton AM. The TALLYHO mouse as a model of human type 2 diabetes. Methods Mol Biol 2012, 933: 75-87.

Kim HY, Stewart TP, Wyatt BN, Siriwardhana N, Saxton AM, Kim JH. Gene expression profiles of a mouse congenic strain carrying an obesity susceptibility QTL under obesigenic diets. Genes & Nutrition 2010, 5: 237-250.

Jacaline K. Parkman, B.S. – Research M.S. student