Clinical & Translational Science

Overview

Translational science is the application of the results from the basic research on cells and animals to the treatment of patients. With rapid developments in technology and genomics, this translational science is changing the advancement of medical care so that prevention and treatment of disease is specific to each individual patient. Much of this personalized medicine is dependent on clinical and translational sciences (CTS). Thus, there is a need for scientists and clinicians who can direct teams in CTS and can establish collaboration among basic and clinical scientists from different disciplines.

Marshall University Joan C. Edwards School of Medicine (JCESOM) equips CTS MS students with the information and training necessary to translate basic advances into improved patient care that will enhance the quality of life for patients in the Appalachian region, particularly southern West Virginia. Graduates of Marshall’s CTS MS program will be able to lead all aspects of clinical trials of new drugs and procedures. This program provides an emphasis on conducting clinical trials specific to the rural regions of West Virginia.


Marshall’s CTS MS program is expanding to meet both the needs of our students and the demands of our economy. Marshall will soon be providing three areas of emphasis within the program: Clinical Trails, Clinical Research, and Clinical Informatics.

Minimum Admission Requirements

Applicants must meet the requirements of both Marshall University Graduate Admissions and the Marshall University Joan C. Edwards School of Medicine Clinical and Translational Sciences Department Admissions Committee. Interested persons may contact the Office of Research and Graduate Education via e-mail at carothers@marshall.edu or phone at (304) 696-7279.

  • Baccalaureate degree from an accredited college or university
  • Prerequisite Coursework (must earn grade of “C” or better):
  • Two semesters of general biology and associated laboratories
  • Two semesters of general chemistry and associated laboratories
  • Two semesters of organic chemistry and associated laboratories
  • Two semesters of physics and associated laboratories
  • One semester of biochemistry
  • Minimum 3.0 GPA overall with a 3.0 for combined science and math courses is recommended. Under certain circumstances, the minimum GPA requirement may be waived on a case by case basis
  • No entrance exam required
  • Interview may be required for admission

Application Deadline

PRIORITY Deadline: June 1 for best chance of admission

Applications are accepted on a rolling basis and are reviewed until the class is filled. Applications will be considered after the priority deadline until June 30, if openings are available.

  • Graduate School Application– http://www.marshall.edu/graduate/select-your-degree-or-certificate-program/how-to-apply-for-admission/. Choose degree seeking then your program.
  • Non-refundable application fee– You should receive an email with a link to submit payment within 24 work hours of submitting your application. If you do not, please e-mail services@marshall.edu for assistance. You may also call to pay over the phone during regular business hours: 304-746-1901.
  • Official transcript from degree-granting institution– May be electronically submitted from your institution’s registrar’s office to services@marshall.edu or mailed directly from that office to: Office of Graduate Admissions, Marshall University, 100 Angus E. Peyton Drive, South Charleston, WV 25303.
  • Written Statement– Your statement should address your educational and career goals and why you should be admitted to the CTS, MS program. Please email it directly to services@marshall.edu in addition to uploading it through the Supplemental Information Form.
  • Supplemental Information Form– Once you choose the program to which you are applying, you will be prompted to upload unofficial documents (i.e. transcript/s, written statement, and résumé/CV).
  • Three Recommendations– Please follow the instructions on the form (accessed through the Supplemental Information Form) and ask your referees to e-mail the letters/forms to ctsms@marshall.edu AND services@marshall.edu

Tuition and Scholarships

Depending on funding, a limited number of scholarships may be available for CTS students. Each scholarship is in the amount of a full year (fall, spring and summer terms) of in-state tuition and fees for the program. Metro, Non-WV residents and international students are eligible for the scholarship; however, the amount provided will remain the same. This is not a tuition remission or a full scholarship, so students may want to contact the Assistant Director of Student Financial Assistance, Cindy Canterberry, MS, at 304-691-8739 or via email madden2@marshall.edu. Applicants may also call the Office of Financial Aid (Link website) to apply for federal or other financial assistance.

Apply Now!

Frequently Asked Questions

Graduates of this program will be able to perform clinical trials, particularly in the rural regions of West Virginia. Graduates also would be strong candidates for positions in schools of medicine and medical centers that have Clinical and Translational Science Centers. There are also opportunities in the pharmaceutical industry or government regulatory bodies.

No entrance exams such as the MCAT or GRE are required at this time.

Prerequisite Coursework (must earn grade of “C” or better):

  • Two semesters of general biology and associated laboratories
  • Two semesters of general chemistry and associated laboratories
  • Two semesters of organic chemistry and associated laboratories
  • Two semesters of physics and associated laboratories
  • One semester of biochemistry

A criminal background check will be required for all students accepted to the program. It must be completed prior to the first day of orientation. Accepted students will receive information for completing this requirement.

Courses may be taught by either MDs or PhDs (or sometimes both), depending on the content of the class.

International students may apply, but preference is given first to in-state applicants and then domestic applicants.

Depending on funding, a limited number of scholarships may be available for CTS students. Each scholarship is in the amount of a full year (fall, spring and summer terms) of in-state tuition and fees for the program. Metro, Non-WV residents and international students are eligible for the scholarship; however, the amount provided will remain the same. This is not a tuition remission or a full scholarship, so students may want to contact the Assistant Director of Student Financial Assistance, Cindy Canterberry, MS, at 304-691-8739 or via email madden2@marshall.edu. Applicants may also call the Office of Financial Aid (Link website) to apply for federal or other financial assistance.

Students can contact the Assistant Director of Student Financial Assistance, Cindy Canterberry, MS, at 304-691-8739 or via email madden2@marshall.edu. Applicants may also call the Office of Financial Aid (Link website) to apply for federal or other financial assistance.

Yes. In addition to the coursework, you will gain experience in of all aspects of clinical trials ranging from regulatory requirements to direct patient interactions. The portion of the trial in which a student begins will determine exactly when the hands-on training will start.

Yes - for one summer only. The program requires CTS650 Rural Clinic Experience during the summer after the first two semesters are complete.

The clinical trials that CTS students participate in will be based on Marshall’s current clinical trials and schedules.

The Co-Directors of the MU JCESOM Graduate Programs are Richard Egleton, PhD at egleton@marshall.edu and Todd Green, PhD at green@marshall.edu.

Clinical science combines research, development and analysis to investigate and evaluate medical treatments and methods under controlled conditions.

Translational science and translational research are merely different names for the same type of work and research.

No, not always. Clinical trials could include other interventions that could have an impact on patients including but not limited to:

  • A medical device (for example a new type of stent)
  • Comparisons of medical procedures (for example MRI versus Cat Scan)
  • Exercise regimens for disease recovery / prevention
  • Diets
  • Use of social media for disease prevention

Class will be held in the Robert C. Byrd Biotechnology Science Center (BBSC), the Charles H. McKown, Jr., MD, Translational Genomic Research Institute (TGRI), or the Erma Ora Byrd Clinical Center (BCC). There is 24 hour/7 day access to the BBSC with Marshall CTS ID, which also functions as a key card.

The normal class size will vary. Some courses will be specific to the CTS students; others will be attended by medical school or biomedical research students.

Lab coats will be provided.

Students will need to provide their own computer, typically a laptop, but not any special equipment or supplies.

Clinical and Translational Science covers a variety of research that is based in the biological aspects of health and disease. Public health science examines the causes and effects of disease and interventions at a “population level,” which both drives the understanding of the most critical issues to research and considers the wide-spread effects of the results of that research. See the Translational Science Spectrum for more information.

Clinical Trials

Below is a list of currently enrolling Clinical Trials at the Appalachian Clinical and Translational Science Institute (ACTSI). If you would like additional information about a specific trial, you can call the contact number provided and speak with a study coordinator.

Additional information about each trial can be obtained at ClinicalTrials.gov by clicking on the descriptions below

Study ID

PI

Description

Contact Information

NCT02329327

Cornell

"A Study in Patients with Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Revers the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (ANNEXA-4)"

Robin Ashford: 304-691-1082

NCT01442194

Ferguson

"Long-term, Prosepctive, Multi- national, parallel-cohort study Monitoring Safety in Patients with MS Newly Started with Fingolimod Once Daily or Treated with Another Approved Disease- Modifying Therapy" CLR1104

Linda Morgan: 304-691-1213

NCT02239120

Nolte

"Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)"

Melissa Marcum: 304-691-8560

Rebecca Smith: 304-691-1834

NCT02477618

Shah

"A Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of SAGE547 Injection in the Treatment of Subjects with Super Refrac-tory Status Epilepticus"

Robin Ashford: 304-691-1082

Doug Melton: 304-691-8618

NCT01797185

Ferguson

"Open-label, safety study of SPARC1104 in Subjects with Spasticity due to MS"

Linda Morgan: 304-691-1213

NCT02373904

Cheung

"A Prospective, Multi-Center Study of the IlluminOSS Photodynamic Bone Sta-bilization System for the Treatment of Impending and Actual Pathological Fractures in the Humerus from Metastatic Bone Disease"

Linda Morgan: 304-691-1213

NCT03114657

Neitch

"A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study of Crenezumab in Patients with Prodromal to Mild Alzheimer's Disease"

Melissa Marcum: 304-691-8560

NCT02792218

Ferguson

"A Randomized, Double-Blind, Double-Dummy, Parallel-Group Study Comparing the Efficacy and Safety of Ofatumumab versus Teriflunomide in Patients with Relapsing Multiple Sclerosis"

Linda Morgan: 304-691-1213

Doug Melton: 304-691-8618

NCT02878330

Lambros

"A Phase 2B Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of MEDI8897, a Mono-clonal Antibody with an Extended Half-Life Against Respiratory Synctial Virus, in Healthy Preterm Infants"

Robin Ashford: 304-691-1082

 

Degree Requirements and Curriculum

Degree Requirements

All students are required to meet the general requirements of the Graduate College for receipt of a master's degree. A minimum of 36 credit hours is required for a non-thesis degree. In addition, all students must pass a written and/or oral comprehensive exam. All students will take the following courses:

Fall Semester I

  • BMS 660 Communication Skills I (1 CR)
  • BMS 680 Biomedical Sciences Seminar (1 CR)
  • CTS 600 Epidemiology and Biostatistics Used in Medical Research (3 CR)
  • CTS 620 Basic Clinical Research Operations (3 CR)
  • CTS 635 Writing and Peer Review of Scientific Publications (1 CR)
  • CTS 640 Clinical Trials Journal Club (1 CR)

Spring Semester I

  • BMS 661 Communication Skills II (1 CR)
  • BMS 680 Biomedical Sciences Seminar (1 CR)
  • CTS 610 Study Design and Applied Statistics in Medical Research (3 CR)
  • CTS 614 Online Survey Tools, Relational and Data Warehousing, and Data Manipulation (3 CR)
  • CTS 630 Fundamentals of Team Science (2 CR)
  • CTS 640 Clinical Trials Journal Club (1 CR)

Summer Term

  • CTS 650 Rural Clinic Experience (5 CR)

Fall Semester II

  • BMS 680 Biomedical Sciences Seminar (1 CR)
  • CTS 625 Clinical Research Operations Lab (5 CR)
  • CTS 640 Clinical Trials Journal Club (1 CR)
  • CTS 660 Molecular Phenotype of Appalachian Disorders (3 CR)

Spring Semester II

  • BMS 680 Biomedical Sciences Seminar (1 CR)
  • CTS 625 Clinical Research Operations Lab (5 CR)
  • CTS 640 Clinical Trials Journal Club (1 CR)

 

Graduates of this program will be able to perform clinical trials, particularly in the rural regions of West Virginia. Graduates also would be strong candidates for positions in schools of medicine and medical centers that have Clinical and Translational Science Centers. There are also opportunities in the pharmaceutical industry or government regulatory bodies.

Additionally, an MS degree in clinical and translational sciences is an absolute requirement for obtaining a National Institutes of Health Clinical and Translational Science Award (CTSA) or an Institutional Development Award.

Leadership and Faculty

Uma Sundaram, MD

Vice Dean, Office of Research & Graduate Education
Phone: (304) 691-1841
sundaramu@marshall.edu

Richard Egleton, PhD

Co-Director, MU JCESOM Graduate Program
Phone: (304) 696-3523
egleton@marshall.edu

Todd L. Green, PhD

Co-Director, MU JCESOM Graduate Program
Phone: (304) 696-3531
green@marshall.edu

Todd Gress, MD, MPH

Assistant Dean & Director, Clinical Research
Phone: (304) 691-8648
gress@marshall.edu

Todd Davies, PhD

Assistant Professor 
Phone: (304) 691-1836
daviest@marshall.edu

Sutoidem M. Akpanudo, MD, PhD, MPH

Associate Professor,
Phone: (304) 691-1000
akpanudo@marshall.edu

Darshana Shah, PhD

Associate Dean, Office of Faculty Affairs & Professional Department
Phone: (304) 691-8639
shah@marshall.edu

Alfred Cecchetti, PhD, MSc, MSc IS

Division Director, Clinical Informatics
Assistant Professor
Phone: (304) 691-1834
cecchetti@marshall.edu