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Clinical Trials

Explore the list of clinical trials currently enrolling at the Marshall Clinical Research Center. To learn more about a specific study, click on the description to view details on ClinicalTrials.gov or contact the listed study coordinator for direct assistance.

Active Clinical Trials

Study ID  PI  Description  Contact Information 
NCT02336217 Dr. Henry Driscoll  Glycemic Emergency Management (GEM); An App for Rapid Response to Hypogycemic and Hyperglycemic Situations (GEMApp)  Dr. Henry Driscoll
NCT03537508 Dr. Jessie Shields Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine when Administered Concomitantly with Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US (MET 42 SANOFI)  Gina Finley, PharmD
NCT03012776 Dr. Nicolas Phan  A Pivotal Study of the Premia Spine TOPS System (TOPS IDE) Jessica Merrick, RN
NCT06063967 Dr. Umapathy Sundaram AFFIRM - Crohn's Disease: Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease Nicole Finley, MSN, RN, ACCNS-AG
NCT06589986 Dr. Umapathy Sundaram AMETRINE-1; A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy with RO7790121 in Patients with Moderately to Severely Active Ulcerative Colitis (GA45329) Nicole Finley, MSN, RN, ACCNS-AG
NCT06388421 Dr. Amro Al-Astal DeciPHer-ILD (GMS-PH-401): A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated with Interstitial Lung Disease (PH-ILD) Amber Vickers, RN
NCT06257875 Dr. Umapathy Sundaram HORIZON: A Multicenter, Randomized Study to Evaluate the Safety and Efficacy of Lutikizumab for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis Nicole Finley, MSN, RN, ACCNS-AG
NCT05686070 Dr. Jorge Lopez OCEANIC STROKE - A multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of ischemic stroke in male and female participants aged 18 years and older after an acute non-cardioembolic ischemic stroke or high-risk TIA Gina Finley, PharmD
Amber Vickers, RN
NCT04396236 Dr. Jorge Lopez PIONEER-PEDS1: Protocol H8H-MC-LAHV(a) Pediatric Options for Migraine Relief: A Randomized, Double-Blind, Placebo-Controlled Study of Lasmiditan for Acute Treatment of Migraine Jessica Merrick, RN
NCT04396574 Dr. Jorge Lopez PIONEER-PEDS2: Protocol H8H-MC-LAHW A Phase 3, 12-Month, Open-Label Study of Lasmiditan in Pediatric Patients with Migraine Jessica Merrick, RN
NCT04965675 Dr. Jorge Lopez PROSPECT II - Interventional, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of IV eptinezumab in adolescents (12-17 years) for the preventive treatment of chronic migraine Jessica Merrick, RN
NCT05643534 Dr. Xavier Villa RALLY - (Ten-01-304) A 12 week, Randomized, Double blind, placebo controlled, phase 3 study to assess the safety and efficacy of a Tenapanor for the treatment of irritable bowel syndrome with constipation (IBS-C) in pediatric patients 12 to less than 18 years old Jessica Merrick, RN
NCT06553547 Dr. Xavier Villa RALLY 202: (Ten-01-202) A 4-Week, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Assess the Safety and Efficacy of Tenapanor for the Treatment of Irritable Bowel Syndrome with Constipation (IBS-C) in Pediatric Patients 6 to Less than 12 Years Old Jessica Merrick, RN
NCT05905926 Dr. Xavier Villa Rall-Y 306: TEN-01-306 An Open-Label Long-Term Safety Study of Tenapanor for the Treatment of Irritable Bowel Syndrome with Constipation (IBS-C) in Pediatric Patients 6 to Less than 18 Years Old Jessica Merrick, RN
NCT05889624 Dr. Jorge Lopez REACH - Responding with Evidence and Access for Childhood Headaches: The REACH Study Hillary Salava, RN
NCT04753385 Dr. Suzanne Holroyd RECOVER: A PRospective, Multi-cEnter, Randomized Controlled Blinded Trial DemOnstrating the Safety and Effectiveness of VNS Therapy® System as AdjunctivE Therapy Versus a No-Stimulation Control in Subjects With Treatment-Resistant Depression Hillary Salava, RN
NCT06305780 Dr. Imran Khawaja RECOVER-AUTONOMIC: A Platform Protocol for Evaluation of Interventions for Autonomic Dysfunction in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) Jessica Merrick, RN
Nicole Finley, MSN, RN, ACCNS-AG
NCT06404047 Dr. Imran Khawaja RECOVER-ENERGIZE: A Platform Protocol for Evaluation of Interventions for Exercise Intolerance in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) Hillary Salava, RN
Nicole Finley, MSN, RN, ACCNS-AG
NCT06404086 Dr. Imran Khawaja RECOVER - Sleep: A Platform Protocol for Evaluation of Interventions for Sleep Disturbances in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) Gina Finley, PharmD
Nicole Finley, MSN, RN, ACCNS-AG
NCT04748601 Dr. Jorge Lopez ROAR - A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 4 Study to Evaluate the Efficacy and Safety of Qudexy® XR in the Prevention of Migraine in Children 6 to 11 Years of Age Nicole Finley, MSN, RN, ACCNS-AG
NCT06819891 Dr. Umapathy Sundaram SIBERITE-2 (GA45332): A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Access the Efficacy and Safety of Induction Therapy with RO7790121 in Patient with Moderately to Severely Active Crohn's Disease Nicole Finley, MSN, RN, ACCNS-AG
NCT06625060 Dr. Jorge Lopez MERANTI- A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults Nicole Finley, MSN, RN, ACCNS-AG

PI Initiated Clinical Trials

IRB Number  PI  Description 
499630 Dr. Alan Koester AVANTA (SRTMMCP)
463451 Dr. Alan Koester AVANTA (SRTMPIP)
451197 Dr. Umapathy Sundaram Marshall University School of Medicine Informatics for Integrating Biology to the Bedside (I2B2)
964144 Dr. Umapathy Sundaram Regulation of intestinal nutrient and electrolyte transport in chronic diseases
2233227 Dr. Jorge Lopez Efficacy and Safety of Greater Occipital Nerve Blocks in Migraine Treatment for Adolescents in a Rural Population
2068017 Dr. Umapathy Sundaram Metabolic Syndrome and colon cancer
2084009 Dr. Umapathy Sundaram Metabolic Syndrome and its Impact on the Incidence and Progression of Barrett's Esophagus and Esophageal Cancer: A Retrospective Study
2272843 Dr. Umapathy Sundaram Metabolic Syndrome and NAFLD/NASH in Appalachian Population

Updated July 2, 2025