Obesity and Related Diseases Cluster

Obesity and Related Diseases Cluster (ORDRC) - Coordinator, Jung Han Kim, PhD

In our modern era, the incidence of obesity has reached epidemic proportions, where over 30% of American adults and 17% of children and teens are obese. In 2017, WV ranked highest for obesity in the U.S. Many obese individuals suffer from related diseases, such as type 2 diabetes, hypertension, and dyslipidemia, leading to a decreased life span. This association of obesity with related metabolic diseases makes obesity a priority public health issue.

Faculty

Basic Science Researcher             Research Interests

Subha Arthur, Ph.D                                Regulation of bile acid absorption in obesity

Yanling Yan, Ph.D                                  Oxidative stress; impaired renal sodium excretion

Travis Salisbury, Ph.D                            Leucine-stimulated induction of mTOR1 in breast cancer in obesity

Maria Serrat, Ph.D                                 Regulation of growth factor transport in bone elongation in childhood obesity

Isabel Larre, Ph.D                                  Regulation of tight junction molecular composition by Na/K-ATPase in obesity

Jung Han Kim, Ph.D                              Genetics of obesity and type 2 diabetes

Nalini Santanam, Ph.D                           Diet, exercise, obesity drugs on cardiometabolic endpoints

Emine Koc, Ph.D                                    Role of mitochondria in obesity disorders

Holly Cyphert, Ph.D                                Molecular regulation of beta cell function

Don Primerano, Ph.D                             Chronic disease susceptibility genes

Jim Denvir, Ph.D                                     Application of multiple hypothesis testing procedures to high-throughput
                                                                genomic data

Hongwei Yu, PhD                                   Microbiome in obesity, diabetes and inflammatory bowel disease

Clinical Researcher                         Research Interests

Uma Sundaram, MD                              Nutrition, inflammatory bowel disease

Joseph Shapiro, MD                              Renal function and hypertension

Omdola Olajide, MD                              Endocrinology and metabolism